Oral Ivacaftor (VX-770) is an investigational drug that is designed to increase the time that activated cystic fibrosis transmembrane conductance regulator (CFTR) protein channels at the cell surface remain open. It has been shown to decrease pulmonary exacerbations and other respiratory symptoms in cystic fibrosis patients It is only to be used in cystic fibrosis … Continue reading

Pediatric Pulmonary Disorders

Possible causes of wheezing in young children. Infants & toddlers have smaller airways RSV Not all wheezing indicates asthma Preferred therapies to treat pediatric asthma Inhaled corticosteroids¬† (drugs of choice) MDI (w/ or w/o spacer/masks) Nebulizers Leukotriene inhibitors¬† (singulair-montelukast) Use as an adjunctive or alternative therapy (some parents like these b/c of PO admin) Long-acting … Continue reading